Investigating the role of non-synonymous variant D67N of ADGRE2 in chronic myeloid leukemia

Investigating the role of non-synonymous variant D67N of ADGRE2 in chronic myeloid leukemia

Abstract Background Chronic myeloid leukaemia (CML) is a type of blood cancer that begins in the hematopoietic stem cells. It is primarily characterized by a specific chromosomal aberration, the Philadelphia chromosome. While the fusion gene is a major contributor to CML, several other genes includi...

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Bibliographic Details
Main Authors: Ayesha Afzal, Harooma Jamshaid, Yasmin Badshah, Maria Shabbir, Janeen H. Trembley, Sameen Zafar, Ghulam Murtaza Kamal, Tayyaba Afsar, Fohad Mabood Husain, Suhail Razak
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
Subjects:
Non-synonymous
CML
Bioinformatics tools
ARMS PCR
In silico analysis
Online Access:https://doi.org/10.1186/s12885-024-13108-6

Internet

https://doi.org/10.1186/s12885-024-13108-6

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