Epac induces ryanodine receptor-dependent intracellular and inter-organellar calcium mobilization in mpkCCD cells

Arginine vasopressin (AVP) induces an increase in intracellular Ca2+ concentration ([Ca2+]i) with an oscillatory pattern in isolated perfused kidney inner medullary collecting duct (IMCD). The AVP-induced Ca2+ mobilization in inner medullary collecting ducts is essential for apical exocytosis and is...

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Bibliographic Details
Main Authors: Kay-Pong Yip, Luisa Ribeiro-Silva, Byeong Cha, Timo Rieg, James S. K. Sham
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1250273/full