Systems metabolic engineering of Escherichia coli for hyper-production of 5‑aminolevulinic acid

Systems metabolic engineering of Escherichia coli for hyper-production of 5‑aminolevulinic acid

Abstract Background 5-Aminolevulinic acid (5-ALA) is a promising biostimulant, feed nutrient, and photodynamic drug with wide applications in modern agriculture and therapy. Although microbial production of 5-ALA has been improved realized by using metabolic engineering strategies during the past fe...

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Bibliographic Details
Main Authors: Wei Pu, Jiuzhou Chen, Yingyu Zhou, Huamin Qiu, Tuo Shi, Wenjuan Zhou, Xuan Guo, Ningyun Cai, Zijian Tan, Jiao Liu, Jinhui Feng, Yu Wang, Ping Zheng, Jibin Sun
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
5‑Aminolevulinic acid
Systems metabolic engineering
Escherichia coli
Synthetic sRNA
Antioxidant defense system
Online Access:https://doi.org/10.1186/s13068-023-02280-9

Internet

https://doi.org/10.1186/s13068-023-02280-9

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