Glucosyl hesperidin exhibits more potent anxiolytic activity than hesperidin accompanied by the attenuation of noradrenaline induction in a zebrafish model

Anxiety is a symptom of various mental disorders, including depression. Severe anxiety can significantly affect the quality of life. Hesperidin (Hes), a flavonoid found in the peel of citrus fruits, reportedly has various functional properties, one of which is its ability to relieve acute and chroni...

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Main Authors: Takumi Nishida, Chihoko Horita, Mikiya Imagawa, Momoka Hibarino, Sayaka Tateno, Yurina Kubo, Momoko Kawabe, Naoki Morishita, Shin Endo, Kazuhiro Shiozaki
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1213252/full