Reduced excitatory neurotransmission in the hippocampus after inflammation and sevoflurane anaesthesia
Background: Inflammation and general anaesthesia likely contribute to perioperative neurocognitive disorders, possibly by causing a neuronal imbalance of excitation and inhibition. We showed previously that treatment with lipopolysaccharide (LPS) and sevoflurane causes a sustained increase in a toni...
Main Authors: | Shahin Khodaei, Dian-Shi Wang, Beverley A. Orser |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | BJA Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772609623000229 |
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