Local absence of secondary structure permits translation of mRNAs that lack ribosome-binding sites.

The initiation of translation is a fundamental and highly regulated process in gene expression. Translation initiation in prokaryotic systems usually requires interaction between the ribosome and an mRNA sequence upstream of the initiation codon, the so-called ribosome-binding site (Shine-Dalgarno s...

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Bibliographic Details
Main Authors: Lars B Scharff, Liam Childs, Dirk Walther, Ralph Bock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3121790?pdf=render