PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea

PSGL-1: a novel immune checkpoint driving T-cell dysfunction in obstructive sleep apnea

IntroductionAlthough higher incidence of cancer represents a major burden for obstructive sleep apnea (OSA) patients, the molecular pathways driving this association are not completely understood. Recently, the adhesion receptor P-selectin glycoprotein-1 (PSGL 1) has been identified as a novel immun...

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Bibliographic Details
Main Authors: Elena Díaz-García, Aldara García-Sánchez, Enrique Alfaro, Cristina López-Fernández, Eva Mañas, Irene Cano-Pumarega, Eduardo López-Collazo, Francisco García-Río, Carolina Cubillos-Zapata
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
PSGL-1
T-cells
immunecheckpoints
sleep apnea
intermittent hypoxia
immune surveillance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277551/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277551/full

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