The TZM-bl Reporter Cell Line Expresses Kynureninase That Can Neutralize 2F5-like Antibodies in the HIV-1 Neutralization Assay

The TZM-bl Reporter Cell Line Expresses Kynureninase That Can Neutralize 2F5-like Antibodies in the HIV-1 Neutralization Assay

Induction of broadly neutralizing antibodies targeting ectodomain of the transmembrane (TM) glycoprotein gp41 HIV-1 provides a basis for the development of a universal anti-viral vaccine. The HeLa cell-derived TZM-bl reporter cell line is widely used for the estimation of lentiviruses neutralization...

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Bibliographic Details
Main Authors: Vladimir Morozov, Sylvie Lagaye, Alexey Morozov
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
TZM-bl cell line
HIV-1
mAb 2F5
mAb 4E10
sera
neutralization assay
Online Access:https://www.mdpi.com/1422-0067/23/2/641

Internet

https://www.mdpi.com/1422-0067/23/2/641

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