Effects of diarylbutane lignans from Schisandra chinensis fruit on SARS-CoV-2 3CLpro and PLpro and their in vitro anti-inflammatory properties

Effects of diarylbutane lignans from Schisandra chinensis fruit on SARS-CoV-2 3CLpro and PLpro and their in vitro anti-inflammatory properties

Background: Schisandra chinensis fruit is a well-known traditional Chinese medicine (TCM), whose extract has a potent inhibitory effect on the severe acute respiratory syndrome-coronavirus-2 (SARS‑CoV‑2) 3-chymotrypsin-like protease (3CLpro) and papain-like protease (PLpro). Purpose: This work aims...

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Bibliographic Details
Main Authors: Bin Li, Liansheng Qiao, Qi Xiao, Jianuo Zhang, Jiushi Liu, Bengang Zhang, Haitao Liu
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Phytomedicine Plus
Subjects:
SARS-CoV-2
3-Chymotrypsin-like protease
Papain-like protease
Schisandra chinensis fruit
Diarylbutane lignans
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031323000283

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http://www.sciencedirect.com/science/article/pii/S2667031323000283

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