Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa
Abstract Background The novel anti-malarial cipargamin (KAE609) has potent, rapid activity against Plasmodium falciparum. Transient asymptomatic liver function test elevations were previously observed in cipargamin-treated subjects in two trials: one in malaria patients in Asia and one in volunteers...
প্রধান লেখক: | , , , , , , , , , , , , , , , , , |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
BMC
2021-12-01
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মালা: | Malaria Journal |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://doi.org/10.1186/s12936-021-04009-1 |