Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells

Spine Metastases in Immunocompromised Mice after Intracardiac Injection of MDA-MB-231-SCP2 Breast Cancer Cells

Breast cancer cells frequently metastasize to bone, where their interaction with bone remodeling cell types enhances osteolytic bone destruction. Importantly, however, whereas skeletal analyses of xenograft models are usually restricted to hindlimb bones, human skeletal metastases are far more frequ...

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Bibliographic Details
Main Authors: Laura Brylka, Katharina Jähn-Rickert, Anke Baranowsky, Mona Neven, Michael Horn, Timur Yorgan, Harriet Wikman, Stefan Werner, Andreas Lübke, Michael Amling, Björn Busse, Klaus Pantel, Thorsten Schinke
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
bone remodeling
breast cancer
Kremen-2
metastasis
spine
Online Access:https://www.mdpi.com/2072-6694/14/3/556

Internet

https://www.mdpi.com/2072-6694/14/3/556

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