HIV infection of thymocytes inhibits IL-7 activity without altering CD127 expression
<p>Abstract</p> <p>Background</p> <p>Thymic function is altered in HIV infection and characterized by dysregulation of the thymic epithelial network, reduced thymic output and ultimately an impaired naïve T-cell pool. The IL-7/IL-7 receptor (IL-7R) signalling pathway is...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-09-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/8/1/72 |