Insights into Inflammatory Priming of Adipose-Derived Mesenchymal Stem Cells: Validation of Extracellular Vesicles-Embedded miRNA Reference Genes as A Crucial Step for Donor Selection

Insights into Inflammatory Priming of Adipose-Derived Mesenchymal Stem Cells: Validation of Extracellular Vesicles-Embedded miRNA Reference Genes as A Crucial Step for Donor Selection

Mesenchymal stem cells (MSCs) are promising tools for cell-based therapies due to their homing to injury sites, where they secrete bioactive factors such as cytokines, lipids, and nucleic acids, either free or conveyed within extracellular vesicles (EVs). Depending on the local environment, MSCs&...

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Bibliographic Details
Main Authors: Enrico Ragni, Paola De Luca, Carlotta Perucca Orfei, Alessandra Colombini, Marco Viganò, Gaia Lugano, Valentina Bollati, Laura de Girolamo
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cells
Subjects:
adipose-mesenchymal stem cells
extracellular vesicles
osteoarthritis
miRNA
reference gene
inflammation
Online Access:https://www.mdpi.com/2073-4409/8/4/369

Internet

https://www.mdpi.com/2073-4409/8/4/369

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