Evaluation of pre-processing methods for tear fluid proteomics using proximity extension assays

Abstract Tear fluid forms a potential source for biomarker identification, and can be minimal invasively collected via Schirmer strips. The lack of knowledge on the processing of Schirmer strips however complicates the analysis and between-study comparisons. We studied two different pre-processing m...

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Bibliographic Details
Main Authors: Daphne P. C. Vergouwen, Amber J. Schotting, Tanja Endermann, Harmen J. G. van de Werken, Dwin G. B. Grashof, Sinthuja Arumugam, Rudy M. M. A. Nuijts, Josianne C. ten Berge, Aniki Rothova, Marco W. J. Schreurs, Marlies Gijs
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31227-1