Pharmacokinetics and pharmacodynamics of intra-articular isoflupredone following administration to horses with lipopolysaccharide-induced synovitis

Abstract Background Intra-articular corticosteroids, such as isoflupredone acetate, are commonly used in the treatment of joint inflammation, especially in performance horses. Following administration in a non-inflamed joints blood concentrations of isoflupredone were low and detectable for only a s...

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Bibliographic Details
Main Authors: Heather K. Knych, Daniel Weiner, Linda Harrison, Daniel S. McKemie
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Veterinary Research
Subjects:
Online Access:https://doi.org/10.1186/s12917-022-03537-5