Radiolabeling and quality control of therapeutic radiopharmaceuticals: optimization, clinical implementation and comparison of radio-TLC/HPLC analysis, demonstrated by [177Lu]Lu-PSMA

Radiolabeling and quality control of therapeutic radiopharmaceuticals: optimization, clinical implementation and comparison of radio-TLC/HPLC analysis, demonstrated by [177Lu]Lu-PSMA

Abstract Background Radiopharmaceuticals are considered as regular medicinal products and therefore the same regulations as for non-radioactive medicinal products apply. However, specific aspects should be considered due to the radiochemical properties. Radiopharmaceutical dedicated monographs are d...

Full description

Bibliographic Details
Main Authors: Eline L. Hooijman, Carolline M. Ntihabose, Thom G. A. Reuvers, Julie Nonnekens, Else A. Aalbersberg, Jordy R. J. P. van de Merbel, Judith E. Huijmans, Stijn L. W. Koolen, Jeroen J. M. A. Hendrikx, Erik de Blois
Format: Article
Language:English
Published: SpringerOpen 2022-11-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Radiopharmaceutical production
Quality control
Radio-TLC analysis
HPLC analysis
[177Lu]Lu-PSMA
Radiolysis
Online Access:https://doi.org/10.1186/s41181-022-00181-0

Internet

https://doi.org/10.1186/s41181-022-00181-0

Similar Items