Identification of Plasmodium vivax proteins with potential role in invasion using sequence redundancy reduction and profile hidden Markov models.

BACKGROUND: This study describes a bioinformatics approach designed to identify Plasmodium vivax proteins potentially involved in reticulocyte invasion. Specifically, different protein training sets were built and tuned based on different biological parameters, such as experimental evidence of secre...

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Bibliographic Details
Main Authors: Daniel Restrepo-Montoya, David Becerra, Juan G Carvajal-Patiño, Alvaro Mongui, Luis F Niño, Manuel E Patarroyo, Manuel A Patarroyo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184965?pdf=render