Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke.

Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke.

Hypercoagulability in sickle cell disease (SCD) is associated with multiple SCD phenotypes, association with stroke risk has not been well described. We hypothesized that serum levels of biomarkers of coagulation activation correlate with high transcranial Doppler ultrasound velocity and decreases w...

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Bibliographic Details
Main Authors: Hyacinth I Hyacinth, Robert J Adams, Charles S Greenberg, Jenifer H Voeks, Allyson Hill, Jacqueline M Hibbert, Beatrice E Gee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4549306?pdf=render

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http://europepmc.org/articles/PMC4549306?pdf=render

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