Longitudinal evaluation of neuroinflammation and oxidative stress in a mouse model of Alzheimer disease using positron emission tomography

Longitudinal evaluation of neuroinflammation and oxidative stress in a mouse model of Alzheimer disease using positron emission tomography

Abstract Background Validation of new biomarkers of Alzheimer disease (AD) is crucial for the successful development and implementation of treatment strategies. Additional to traditional AT(N) biomarkers, neuroinflammation biomarkers, such as translocator protein (TSPO) and cystine/glutamine antipor...

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Bibliographic Details
Main Authors: Luka Rejc, Vanessa Gómez-Vallejo, Ana Joya, Gemma Arsequell, Ander Egimendia, Pilar Castellnou, Xabier Ríos-Anglada, Unai Cossío, Zuriñe Baz, Leyre Iglesias, Estibaliz Capetillo-Zarate, Pedro Ramos-Cabrer, Abraham Martin, Jordi Llop
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
TSPO
Oxidative stress
Positron emission tomography
Alzheimer disease
Online Access:https://doi.org/10.1186/s13195-022-01016-5

Internet

https://doi.org/10.1186/s13195-022-01016-5

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