Fecal microbial transplantation limits neural injury severity and functional deficits in a pediatric piglet traumatic brain injury model

Fecal microbial transplantation limits neural injury severity and functional deficits in a pediatric piglet traumatic brain injury model

Pediatric traumatic brain injury (TBI) is a leading cause of death and disability in children. Due to bidirectional communication between the brain and gut microbial population, introduction of key gut bacteria may mitigate critical TBI-induced secondary injury cascades, thus lessening neural damage...

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Bibliographic Details
Main Authors: Madison M. Fagan, Christina B. Welch, Kelly M. Scheulin, Sydney E. Sneed, Julie H. Jeon, Morgane E. Golan, Savannah R. Cheek, Deborah A. Barany, Georg Oeltzschner, Todd R. Callaway, Qun Zhao, Hea Jin Park, Jeferson M. Lourenco, Kylee J. Duberstein, Franklin D. West
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Neuroscience
Subjects:
traumatic brain injury
porcine (pig) model
fecal matter transfer
MRI
microbiome gut-brain axis
behavior analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1249539/full

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https://www.frontiersin.org/articles/10.3389/fnins.2023.1249539/full

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