Residual Foci of DNA Damage Response Proteins in Relation to Cellular Senescence and Autophagy in X-Ray Irradiated Fibroblasts

Residual Foci of DNA Damage Response Proteins in Relation to Cellular Senescence and Autophagy in X-Ray Irradiated Fibroblasts

DNA repair (DNA damage) foci observed 24 h and later after irradiation are called “residual” in the literature. They are believed to be the repair sites for complex, potentially lethal DNA double strand breaks. However, the features of their post-radiation dose-dependent quantitative changes and the...

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Bibliographic Details
Main Authors: Andrey Osipov, Anna Chigasova, Elizaveta Yashkina, Maxim Ignatov, Yuriy Fedotov, Daria Molodtsova, Natalia Vorobyeva, Andreyan N. Osipov
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
DNA double strand breaks
DNA damage response
residual DNA repair foci
cellular senescence
autophagy
caspase-3
Online Access:https://www.mdpi.com/2073-4409/12/8/1209

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https://www.mdpi.com/2073-4409/12/8/1209

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