Prothrombin Time, Activated Partial Thromboplastin Time, and Fibrinogen Reference Intervals for Inbred Strain 13/N Guinea Pigs (<i>Cavia porcellus</i>) and Validation of Low Volume Sample Analysis

Inbred strain 13/N guinea pigs are used as small animal models for the study of hemorrhagic fever viruses. Coagulation abnormalities, including prolonged clotting times and bleeding, are characteristic of hemorrhagic fever in humans; patients often meet criteria for disseminated intravascular coagul...

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Bibliographic Details
Main Authors: Jillian A. Condrey, Timothy Flietstra, Kaitlyn M. Nestor, Elizabeth L. Schlosser, JoAnn D. Coleman-McCray, Sarah C. Genzer, Stephen R. Welch, Jessica R. Spengler
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/8/8/1127