Hippo signaling controls cell cycle and restricts cell plasticity in planarians.

The Hippo pathway plays a key role in regulating cell turnover in adult tissues, and abnormalities in this pathway are consistently associated with human cancers. Hippo was initially implicated in the control of cell proliferation and death, and its inhibition is linked to the expansion of stem cell...

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Bibliographic Details
Main Authors: Nídia de Sousa, Gustavo Rodríguez-Esteban, Jose Ignacio Rojo-Laguna, Emili Saló, Teresa Adell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5794332?pdf=render