3506 PRMT5 is a novel therapeutic target to enhance radiation therapy for cancer treatment
OBJECTIVES/SPECIFIC AIMS: Prostate cancer is the second leading cause of cancer-related death among men in the U.S. and over half of all prostate cancer patients receive radiation therapy (RT). RT induces double-strand breaks (DSBs) in DNA which are lethal to cells if not repaired. While potentially...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2019-03-01
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Series: | Journal of Clinical and Translational Science |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866119002577/type/journal_article |