Pathogenic Variant Spectrum in Breast Cancer Risk Genes in Finnish Patients

Pathogenic Variant Spectrum in Breast Cancer Risk Genes in Finnish Patients

Recurrent pathogenic variants have been detected in several breast and ovarian cancer (BC/OC) risk genes in the Finnish population. We conducted a gene-panel sequencing and copy number variant (CNV) analysis to define a more comprehensive spectrum of pathogenic variants in <i>BRCA1</i>,...

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Bibliographic Details
Main Authors: Anna K. Nurmi, Maija Suvanto, Joe Dennis, Kristiina Aittomäki, Carl Blomqvist, Heli Nevanlinna
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
breast cancer
pathogenic variant
gene-panel sequencing
copy number variant
<i>BRCA1</i>
<i>BRCA2</i>
Online Access:https://www.mdpi.com/2072-6694/14/24/6158

Internet

https://www.mdpi.com/2072-6694/14/24/6158

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