TGF-beta Sma/Mab signaling mutations uncouple reproductive aging from somatic aging.
Female reproductive cessation is one of the earliest age-related declines humans experience, occurring in mid-adulthood. Similarly, Caenorhabditis elegans' reproductive span is short relative to its total life span, with reproduction ceasing about a third into its 15-20 day adulthood. All of th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-12-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2791159?pdf=render |