Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels

Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels

Mutations that modulate the activity of ion channels are essential tools to understand the biophysical determinants that control their gating. Here authors reveal the role played by a single residue in the second transmembrane domain of vertebrate and invertebrate two-pore domain potassium channels.

Bibliographic Details
Main Authors: Ismail Ben Soussia, Sonia El Mouridi, Dawon Kang, Alice Leclercq-Blondel, Lamyaa Khoubza, Philippe Tardy, Nora Zariohi, Marie Gendrel, Florian Lesage, Eun-Jin Kim, Delphine Bichet, Olga Andrini, Thomas Boulin
Format: Article
Language:English
Published: Nature Portfolio 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08710-3

Internet

https://doi.org/10.1038/s41467-019-08710-3

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