Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
Mutations that modulate the activity of ion channels are essential tools to understand the biophysical determinants that control their gating. Here authors reveal the role played by a single residue in the second transmembrane domain of vertebrate and invertebrate two-pore domain potassium channels.
Bibliographic Details
| Main Authors: |
Ismail Ben Soussia,
Sonia El Mouridi,
Dawon Kang,
Alice Leclercq-Blondel,
Lamyaa Khoubza,
Philippe Tardy,
Nora Zariohi,
Marie Gendrel,
Florian Lesage,
Eun-Jin Kim,
Delphine Bichet,
Olga Andrini,
Thomas Boulin |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2019-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-019-08710-3
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