SOD1 mRNA expression in sporadic amyotrophic lateral sclerosis

SOD1 mRNA expression in sporadic amyotrophic lateral sclerosis

The mutated Cu,Zn-superoxide dismutase gene (SOD1) (E.C. No. 1.15.1.1) is generally recognized as a pathological cause of 20% of the familial form of Amyotrophic Lateral Sclerosis (ALS). However, several pieces of evidence also show that wild-type SOD1, under conditions of cellular stress, is implic...

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Bibliographic Details
Main Authors: Stella Gagliardi, Emanuela Cova, Annalisa Davin, Stefania Guareschi, Kenneth Abel, Elena Alvisi, Umberto Laforenza, Roberta Ghidoni, John Richard Cashman, Mauro Ceroni, Cristina Cereda
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Neurobiology of Disease
Subjects:
SOD1
Amyotrophic lateral sclerosis
mRNA
Spinal cord
Brain stem
Cerebellum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110001051

Internet

http://www.sciencedirect.com/science/article/pii/S0969996110001051

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