Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet.

Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet.

BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease. Insulin resistance (IR) appears to be critical in its pathogenesis. We evaluated the effects of sodium butyrate (butyrate) and its synthetic derivative N-(1-carbamoyl-2-phenyl-ethyl) but...

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Bibliographic Details
Main Authors: Giuseppina Mattace Raso, Raffaele Simeoli, Roberto Russo, Anna Iacono, Anna Santoro, Orlando Paciello, Maria Carmela Ferrante, Roberto Berni Canani, Antonio Calignano, Rosaria Meli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3702592?pdf=render

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http://europepmc.org/articles/PMC3702592?pdf=render

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