Genomic study of Acinetobacter baumannii strains co-harboring blaOXA-58 and blaNDM-1 reveals a large multidrug-resistant plasmid encoding these carbapenemases in Brazil

Genomic study of Acinetobacter baumannii strains co-harboring blaOXA-58 and blaNDM-1 reveals a large multidrug-resistant plasmid encoding these carbapenemases in Brazil

IntroductionAcinetobacter baumannii contributes significantly to the global issue of multidrug-resistant (MDR) nosocomial infections. Often, these strains demonstrate resistance to carbapenems (MDR-CRAB), the first-line treatment for infections instigated by MDR A. baumannii. Our study focused on th...

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Bibliographic Details
Main Authors: Daiana Cristina Silva Rodrigues, Melise Chaves Silveira, Bruno Rocha Pribul, Bruna Ribeiro Sued Karam, Renata Cristina Picão, Gabriela Bergiante Kraychete, Felicidade Mota Pereira, Rildo Mendes de Lima, Antonio Kleber Gomes de Souza, Robson Souza Leão, Elizabeth Andrade Marques, Cláudio Marcos Rocha-de-Souza, Ana Paula D'Alincourt Carvalho-Assef
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Microbiology
Subjects:
Acinetobacter baumannii
OXA-58 carbapenemase
NDM-1 carbapenemase
genomic
plasmids
co-harboring
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1439373/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1439373/full

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