Utilization of macrocyclic peptides to target protein-protein interactions in cancer

Protein-protein interactions (PPIs) play vital roles in normal cellular processes. Dysregulated PPIs are involved in the process of various diseases, including cancer. Thus, these PPIs may serve as potential therapeutic targets in cancer treatment. However, despite rapid advances in small-molecule d...

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Bibliographic Details
Main Authors: Jiawen Yang, Qiaoliang Zhu, Yifan Wu, Xiaojuan Qu, Haixia Liu, Biao Jiang, Di Ge, Xiaoling Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.992171/full