GAS5 regulated by FTO-mediated m6A modification suppresses cell proliferation via the IGF2BP2/QKI axis in breast cancer

Abstract Background The lncRNA growth arrest-specific 5 (GAS5) is involved in regulating breast cancer progression. In this study, we aimed to elucidate the function and mechanism of GAS5 in breast cancer. Methods The expressions of GAS5, fat mass and obesity-associated protein (FTO), insulin-like g...

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Bibliographic Details
Main Authors: Yuzhao Yan, Jing Ma, Qingqiu Chen, Ting Zhang, Rui Fan, Junze Du
Format: Article
Language:English
Published: Springer 2024-05-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-024-01051-8