Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the <i>mdx-4cv</i> Model of Duchenne Muscular Dystrophy

Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the <i>mdx-4cv</i> Model of Duchenne Muscular Dystrophy

Extraocular muscles (EOMs) represent a specialized type of contractile tissue with unique cellular, physiological, and biochemical properties. In Duchenne muscular dystrophy, EOMs stay functionally unaffected in the course of disease progression. Therefore, it was of interest to determine their prot...

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Bibliographic Details
Main Authors: Stephen Gargan, Paul Dowling, Margit Zweyer, Jens Reimann, Michael Henry, Paula Meleady, Dieter Swandulla, Kay Ohlendieck
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Life
Subjects:
Duchenne muscular dystrophy
dystrophinopathy
extraocular muscle
glyceraldehyde-3-phosphate dehydrogenase
myosin-14
myosin heavy chain
Online Access:https://www.mdpi.com/2075-1729/11/7/595

Internet

https://www.mdpi.com/2075-1729/11/7/595

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