ZNF283, a Krüppel-associated box zinc finger protein, inhibits RNA synthesis of porcine reproductive and respiratory syndrome virus by interacting with Nsp9 and Nsp10

ZNF283, a Krüppel-associated box zinc finger protein, inhibits RNA synthesis of porcine reproductive and respiratory syndrome virus by interacting with Nsp9 and Nsp10

Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) is a viral pathogen with substantial economic implications for the global swine industry. The existing vaccination strategies and antiviral drugs offer limited protection. Replication of the viral RNA genome encompasses a complex s...

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Bibliographic Details
Main Authors: Heyou Yi, Ruirui Ye, Ermin Xie, Lechen Lu, Qiumei Wang, Shaojun Wang, Yankuo Sun, Tao Tian, Yingwu Qiu, Qianwen Wu, Guihong Zhang, Heng Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Veterinary Research
Subjects:
Porcine reproductive and respiratory syndrome virus
Krüppel-associated box zinc finger protein
ZNF283
antiviral
Online Access:https://doi.org/10.1186/s13567-023-01263-w

Internet

https://doi.org/10.1186/s13567-023-01263-w

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