The Pseudomonas aeruginosa ExoY phenotype of high-copy-number recombinants is not detectable in natural isolates

The nucleotidyl cyclase ExoY is an effector protein of the type III secretion system of Pseudomonas aeruginosa. We compared the cyclic nucleotide production and lung disease phenotypes caused by the ExoY-overexpressing strain PA103ΔexoUexoT::Tc pUCPexoY, its vector control strain PA103ΔexoUexoT::Tc...

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Bibliographic Details
Main Authors: Antje Munder, Justin Rothschuh, Bastian Schirmer, Jens Klockgether, Volkhard Kaever, Burkhard Tümmler, Roland Seifert, Christina Kloth
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170250