Osteomacs interact with megakaryocytes and osteoblasts to regulate murine hematopoietic stem cell function

Abstract: Networking between hematopoietic stem cells (HSCs) and cells of the hematopoietic niche is critical for stem cell function and maintenance of the stem cell pool. We characterized calvariae-resident osteomacs (OMs) and their interaction with megakaryocytes to sustain HSC function and identi...

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Bibliographic Details
Main Authors: Safa F. Mohamad, Linlin Xu, Joydeep Ghosh, Paul J. Childress, Irushi Abeysekera, Evan R. Himes, Hao Wu, Marta B. Alvarez, Korbin M. Davis, Alexandra Aguilar-Perez, Jung Min Hong, Angela Bruzzaniti, Melissa A. Kacena, Edward F. Srour
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920300847