Cryptopatches Are Essential for the Development of Human GALT
Abnormal gut-associated lymphoid tissue (GALT) in humans is associated with infectious and autoimmune diseases, which cause dysfunction of the gastrointestinal (GI) tract immune system. To aid in investigating GALT pathologies in vivo, we bioengineered a human-mouse chimeric model characterized by t...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-06-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713002702 |