Cryptopatches Are Essential for the Development of Human GALT

Cryptopatches Are Essential for the Development of Human GALT

Abnormal gut-associated lymphoid tissue (GALT) in humans is associated with infectious and autoimmune diseases, which cause dysfunction of the gastrointestinal (GI) tract immune system. To aid in investigating GALT pathologies in vivo, we bioengineered a human-mouse chimeric model characterized by t...

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Bibliographic Details
Main Authors:	Tomonori Nochi, Paul W. Denton, Angela Wahl, J. Victor Garcia
Format:	Article
Language:	English
Published:	Elsevier 2013-06-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124713002702

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