Bystander effect of SARS-CoV-2 spike protein on human monocytic THP-1 cell activation and initiation of prothrombogenic stimulus representing severe COVID-19
Abstract Background Hypercoagulable state and thromboembolic complications are potential life-threatening events in COVID-19 patients. Our previous studies demonstrated that SARS-CoV-2 infection as well as viral spike protein expressed epithelial cells exhibit senescence with the release of inflamma...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Journal of Inflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12950-022-00325-8 |