A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity

A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity

Abstract The blood–brain barrier is playing a critical role in controlling the influx and efflux of biological substances essential for the brain’s metabolic activity as well as neuronal function. Thus, the functional and structural integrity of the BBB is pivotal to maintain the homeostasis of the...

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Bibliographic Details
Main Authors: Hossam Kadry, Behnam Noorani, Luca Cucullo
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Fluids and Barriers of the CNS
Subjects:
Blood–brain barrier
Tight junctions
Transcytosis
Disruption
Permeability
Markers
Online Access:http://link.springer.com/article/10.1186/s12987-020-00230-3

Internet

http://link.springer.com/article/10.1186/s12987-020-00230-3

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