Osteogenic niche in the regulation of normal hematopoiesis and leukemogenesis
The bone marrow microenvironment, also known as the bone marrow niche, is a complex network of cell types and acellular factors that supports normal hematopoiesis. For many years, leukemia was believed to be caused by a series of genetic hits to hematopoietic stem and progenitor cells, which transfo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2018-12-01
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| Series: | Haematologica |
| Online Access: | https://haematologica.org/article/view/8690 |