Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population

Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population

Abstract Background Severe neonatal hyperbilirubinemia could lead to kernicterus and neonatal death. This study aimed to analyze the association between single nucleotide polymorphisms in genes involved in bilirubin metabolism and the incidence of severe hyperbilirubinemia. Methods A total of 144 ne...

Full description

Bibliographic Details
Main Authors: Juan Fan, Hua-Yun He, Huan-Huan Li, Pi-Liu Wu, Lei Tang, Bo-Yin Deng, Wen-Hui Dong, Jian-Hui Wang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Pediatrics
Subjects:
Single nucleotide polymorphism
UGT1A1
SLCO1B3
Neonatal hyperbilirubinemia
Online Access:https://doi.org/10.1186/s12887-024-04537-0

Internet

https://doi.org/10.1186/s12887-024-04537-0

Similar Items