Prognostic landscape of mitochondrial genome in myelodysplastic syndrome after stem-cell transplantation

Prognostic landscape of mitochondrial genome in myelodysplastic syndrome after stem-cell transplantation

Abstract Despite mitochondrial DNA (mtDNA) mutations are common events in cancer, their global frequency and clinical impact have not been comprehensively characterized in patients with myelodysplastic neoplasia (also known as myelodysplastic syndromes, MDS). Here we performed whole-genome sequencin...

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Bibliographic Details
Main Authors: Jing Dong, Christopher Staffi Buradagunta, Tao Zhang, Stephen Spellman, Yung-Tsi Bolon, Amy E. DeZern, Shahinaz M. Gadalla, H. Joachim Deeg, Aziz Nazha, Corey Cutler, Chao Cheng, Raul Urrutia, Paul Auer, Wael Saber
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Hematology & Oncology
Subjects:
Mitochondrial genome
Allogeneic hematopoietic stem-cell transplantation
Myelodysplastic syndromes
Prognosis
Whole-genome sequencing
Online Access:https://doi.org/10.1186/s13045-023-01418-4

Internet

https://doi.org/10.1186/s13045-023-01418-4

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