Capturing native interactions: intrinsic methods to study chromatin conformation
The 3D organization of chromatin controls gene expression through spatial interactions between genomic loci. FISH and 3C‐based methods that are commonly used to study chromatin organization utilize chemical crosslinking, a step that may introduce biases in detectable chromatin interactions. In their...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2016-12-01
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| Series: | Molecular Systems Biology |
| Online Access: | https://doi.org/10.15252/msb.20167438 |