Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington’s Disease

Fibroblast Growth Factor 9 Suppresses Striatal Cell Death Dominantly Through ERK Signaling in Huntington’s Disease

Background/Aims: Huntington’s disease (HD) is a heritable neurodegenerative disorder, and there is no cure for HD to date. A type of fibroblast growth factor (FGF), FGF9, has been reported to play prosurvival roles in other neurodegenerative diseases, such as Parkinson’s disease and Alzheimer’s dise...

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Bibliographic Details
Main Authors: Issa Olakunle Yusuf, Pei-Hsun Cheng, Hsiu-Mei Chen, Yu-Fan Chang, Chih-Yi Chang, Han-In Yang, Chia-Wei Lin, Shaw-Jenq Tsai, Jih-Ing Chuang, Chia-Ching Wu, Bu-Miin Huang, H. Sunny Sun, Shang-Hsun Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Fibroblast Growth Factor 9
Striatal cell death
Cell signaling
Glial cell line-derived neurotrophic factor
Huntington’s disease
Online Access:https://www.karger.com/Article/FullText/491889

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https://www.karger.com/Article/FullText/491889

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