Metformin prevents the pathological browning of subcutaneous white adipose tissue

Objective: Browning, the conversion of white adipose tissue (WAT) to a beige phenotype, has gained interest as a strategy to induce weight loss and improve insulin resistance in metabolic disorders. However, for hypermetabolic conditions stemming from burn trauma or cancer cachexia, browning is thou...

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Bibliographic Details
Main Authors: Christopher Auger, Carly M. Knuth, Abdikarim Abdullahi, Osai Samadi, Alexandra Parousis, Marc G. Jeschke
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819306192