Mitoxantrone Quantification by HPLC-MS/MS in Caco-2 Culture Media
Mitoxantrone is a marker substrate of breast cancer resistance protein (BCRP). BCRP is involved in a number of pharmacokinetic drug-drug interactions. The transporter’s possible saturability makes it advisable to use low concentrations of mitoxantrone for in vitro studies. Consequently, mitoxantrone...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
NEICON ISP LLC
2023-03-01
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| Series: | Ведомости Научного центра экспертизы средств медицинского применения |
| Subjects: | |
| Online Access: | https://www.vedomostincesmp.ru/jour/article/view/449 |