Increased prevalence of the <it>pfdhfr/phdhps </it>quintuple mutant and rapid emergence of <it>pfdhps </it>resistance mutations at codons 581 and 613 in Kisumu, Kenya

<p>Abstract</p> <p>Background</p> <p>Anti-malarial drug resistance in Kenya prompted two drug policy changes within a decade: sulphadoxine-pyrimethamine (SP) replaced chloroquine (CQ) as the first-line anti-malarial in 1998 and artemether-lumefantrine (AL) replaced SP i...

Full description

Bibliographic Details
Main Authors: Prigge Sean T, Bedno Sheryl A, Akala Hoseah M, Eyase Fredrick L, Spalding Maroya D, Coldren Rodney L, Moss William J, Waters Norman C
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/9/1/338