A gene signature is critical for intrahepatic cholangiocarcinoma stem cell self-renewal and chemotherapeutic response

A gene signature is critical for intrahepatic cholangiocarcinoma stem cell self-renewal and chemotherapeutic response

Abstract Background Improved understanding of the stemness regulation mechanism in intrahepatic cholangiocarcinoma (ICC) could identify targets and guidance for adjuvant transarterial chemoembolization (TACE). Methods TCGA database was excavated to identify the ICC stemness-associated genes. The pro...

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Bibliographic Details
Main Authors: Lifeng Huang, Dongwei Xu, Yawei Qian, Xiaoqiang Zhang, Han Guo, Meng Sha, Rui Hu, Xiaoni Kong, Qiang Xia, Yi Zhang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
Cancer stem cells
Intrahepatic cholangiocarcinoma
Methionine cycle
Adjuvant chemotherapeutics
Prognosis
Online Access:https://doi.org/10.1186/s13287-022-02988-9

Internet

https://doi.org/10.1186/s13287-022-02988-9

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